Article

Virus-against-virus dominant-negative interference strategy targeting a viral CC chemokine prevents cytomegalovirus-related neurodevelopmental pathogenesis

2025-02-12

Abstract excerpt

<h4>Background</h4> Congenital cytomegalovirus (CMV) infections are one leading cause of human neurodevelopmental disorders. Increasing evidence for the pathogenic involvement of brain immune alterations was obtained in the recent years. Host and virus-encoded chemokines might play important roles in CMV-related neuropathogenesis by regulating leukocyte trafficking and microglia recruitment in the CMV-infected br...

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Literature Corpus work: c747b705-0784-5951-bf3d-3f7c6b5d3da2
DOI: 10.1101/2025.02.11.637423

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