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Article

High susceptibility of FVB/N mice to the paralytic disease induced by ts1, a mutant of Moloney murine leukemia virus TB.

Virology - 1 Jan 1991

Wong P K, Floyd E, Szurek P F

Abstract excerpt

The ts1 mutant of Moloney murine leukemia virus TB causes a degenerative neurologic and immunologic disease in susceptible strains of mice. This disease syndrome is characterized by development of spongiform encephalomyelopathy resulting in hindlimb paralysis, generalized bodywasting, and marked...

Topics

Aging
Animals
Brain
Disease Susceptibility
Hybridization, Genetic
Mice
Mice, Inbred BALB C
Moloney murine leukemia virus
Mutation
Paralysis
Spinal Cord
Spleen
Thymus Gland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virulence

Virus Replication

Source

Identifiers

PMID: 1984656
DOI: 10.1016/0042-6822(91)90041-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1984656-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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