Article
Lymphatic dissemination and comparative pathology of recombinant measles viruses in genetically modified mice.
Journal of virology - 1 Feb 2000
Mrkic B, Odermatt B, Klein M A, Billeter M A, Pavlovic J, Cattaneo R
Abstract excerpt
The dissemination of the Edmonston measles virus (Ed-MV) vaccine strain was studied with genetically modified mice defective for the alpha/beta interferon receptor and expressing human CD46 with human-like tissue specificity and efficiency. A few days after intranasal infection, macrophages expressing Ed-MV RNA were detected in the lungs, in draining lymph nodes, and in the thymus. In lymph nodes, large syncytia...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
