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Cytomegalovirus Cell Tropism, Replication, and Gene Transfer in Brain

15 Dec 1999

Abstract excerpt

Cytomegalovirus (CMV) infects a majority of adult humans. During early development and in the immunocompromised adult, CMV causes neurological deficits. We used recombinant murine cytomegalovirus (mCMV) expressing either green fluorescent protein (GFP) or beta-galactosidase under control of human elongation factor 1 promoter or CMV immediate early-1 promoter as reporter genes for infected brain cells. In vivo and...

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PMID: 10594076
DOI: 10.1523/jneurosci.19-24-10948.1999

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