Article
[Genetic polymorphism of acetylation and hydroxylation in the Briton population].
Therapie - 1 Jan 2000
Bressollette L, Berthou F, Riche C, Mottier D, Floch H H
Abstract excerpt
Genetic-controlled drug oxidation and acetylation were studied using dextromethorphan and caffeine as test compounds respectively in white Briton subjects (41 Britons and 27 Bigoudens considered as an ethnic group). Phenotyping was performed using the metabolic ratio (MR) calculated as the urinary output dextromethorphan/dextrorphan ratio and the urinary output of 5-acetylamino-6-formylamino-3-methyluracil...
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