[Genetic polymorphism of acetylation and hydroxylation in the Briton population].

Article

[Genetic polymorphism of acetylation and hydroxylation in the Briton population].

Therapie - 1 Jan 2000

Bressollette L, Berthou F, Riche C, Mottier D, Floch H H

Abstract excerpt

Genetic-controlled drug oxidation and acetylation were studied using dextromethorphan and caffeine as test compounds respectively in white Briton subjects (41 Britons and 27 Bigoudens considered as an ethnic group). Phenotyping was performed using the metabolic ratio (MR) calculated as the urinar...

Topics

Acetylation
Ethnicity
Female
France
Genetics, Population
Humans
Hydroxylation
Liver
Male
Pharmaceutical Preparations
Phenotype
Polymorphism, Genetic

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