Article
Genetic polymorphisms in IGF-I and IGFBP-3 are associated with prostate cancer in the Chinese population.
PloS one - 1 Jan 2014
Qian Jian, Zhou Hai, Chen Jiawei, Ding Qi, Cao Qiang, Qin Chao, Shao Pengfei, Li Pu, Cai Hongzhou, Meng Xiaoxin, Ju Xiaobing, Wang Meilin, Zhang Zhengdong, Li Jie, Hua Lixin, Yin Changjun
Abstract excerpt
Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3) are members of the insulin-like growth factor (IGF) family that play important roles in carcinogenesis. We hypothesized that the functional polymorphisms in IGF-I and IGFBP-3 may be associated with the risk of prostate cancer (PCa) in the Chinese population. This hospital-based case-control study included 664 PCa patients and 702 cancer-free...
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