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Article

Optical control of ligand-gated ion channels.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Szobota Stephanie, McKenzie Catherine, Janovjak Harald

Abstract excerpt

In the vibrant field of optogenetics, optics and genetic targeting are combined to commandeer cellular functions, such as the neuronal action potential, by optically stimulating light-sensitive ion channels expressed in the cell membrane. One broadly applicable manifestation of this approach are covalently attached photochromic tethered ligands (PTLs) that allow activating ligand-gated ion channels with...

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PMID: 23529448
DOI: 10.1007/978-1-62703-351-0_32

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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