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Article

Allosteric regulation in NMDA receptors revealed by the genetically encoded photo-cross-linkers.

Scientific reports - 7 Oct 2016

Tian Meilin, Ye Shixin

Abstract excerpt

Allostery is essential to neuronal receptor function, but its transient nature poses a challenge for characterization. The N-terminal domains (NTDs) distinct from ligand binding domains are a major locus for allosteric regulation of NMDA receptors (NMDARs), where different modulatory binding sites have been observed. The inhibitor ifenprodil, and related phenylethanoamine compounds specifically targeting...

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Identifiers

PMID: 27713495
DOI: 10.1038/srep34751
PMCID: PMC5054432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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