A CRISPR view of development.

doi:10.1101/gad.248252.114

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Article

A CRISPR view of development.

Genes & development - 1 Sept 2014

Harrison Melissa M, Jenkins Brian V, O'Connor-Giles Kate M, Wildonger Jill

Abstract excerpt

The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9 (CRISPR-associated nuclease 9) system is poised to transform developmental biology by providing a simple, efficient method to precisely manipulate the genome of virtually any developing organism. This RNA-guided nuclease (...

Topics

Animals
CRISPR-Associated Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Expression Regulation, Developmental
Genome
Humans
Mutation
RNA Editing
RNA, Small Untranslated

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