Article
Evolution of aneuploidy up to Day 4 of human preimplantation development
22 Mar 2013
Abstract excerpt
STUDY QUESTION: What is the incidence of aneuploidy and mosaicism in all cells of top-quality Day-4 embryos analysed by array-based comparative genomic hybridization (array CGH)? SUMMARY ANSWER: Our data show extensive abnormalities in Day-4 embryos. WHAT IS KNOWN ALREADY: Numerous studies on human embryos at Day 3 and Day 5 of development show that they frequently contain aneuploid cells and are mosaic, although...
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