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Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos

9 Oct 2012

Abstract excerpt

STUDY QUESTION: What are the aneuploidy rates and incidence of mosaicism in good-quality human preimplantation embryos. SUMMARY ANSWER: High-level mosaicism and structural aberrations are not restricted to arrested or poorly developing embryos but are also common in good-quality IVF embryos. WHAT IS KNOWN ALREADY: Humans, compared with other mammals, have a poor fertility rate, and even IVF treatments have a...

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PMID: 23054067
DOI: 10.1093/humrep/des362

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