Analysis of the evolution of chromosome abnormalities in human embryos from Day 3 to 5 using CGH and FISH

Abstract excerpt

The use of interphase fluorescent in situ hybridization (FISH) has shown that a large number of human embryos exhibit chromosomal abnormalities in vitro. The most common abnormality is mosaicism which is seen in up to 50% of preimplantation embryos at all stages of development. In this study, comparative genomic hybridization (CGH) was used to analyse 1-2 cells biopsied on Day 3 of development while the rest of...

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• Share to Chromosomal and Genetic Variations
• Share to Genomic variations and chromosomal abnormalities
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