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Article

Aneuploidy in the Human Cleavage Stage Embryo

1 Jan 2011

Abstract excerpt

The cleavage stage embryo (days 1-3) stands out due to the high level of chromosomal anomalies, especially mosaicism that arises prior to global embryonic genome activation. Molecular cytogenetic studies show that an average of 60% of in vitro derived embryos have at least one aneuploid cell by the time they are 3 days old. However, comprehensive studies of the chromosome content of individual cells have revealed...

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Share to Genomic variations and chromosomal abnormalities
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PMID: 21293113
DOI: 10.1159/000323794

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