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The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos

2 Jun 2010

Abstract excerpt

BACKGROUND: Post-zygotic chromosome segregation errors are very common in human embryos after in vitro fertilization, resulting in mosaic embryos. However, the significance of mosaicism for the developmental potential of early embryos is unknown. We assessed chromosomal constitution and development of embryos from compaction to the peri-implantation stage. METHODS: From 112 cryopreserved Day 4 human embryos...

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PMID: 20519247
DOI: 10.1093/humrep/deq139

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