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Article

CD247 variants and single-nucleotide polymorphisms observed in systemic lupus erythematosus patients.

Rheumatology (Oxford, England) - 1 Sept 2013

Takeuchi Tsutomu, Suzuki Katsuya

Abstract excerpt

SLE is associated with a deficiency in cluster of differentiation 247 (CD247, also known as CD3 zeta chain), a component of the T-cell receptor (TCR)-CD3 complex. A comprehensive analysis showed that in more than half of SLE patients tested CD247 expression was either attenuated or absent. Recent evidence suggests that these variations in expression profiles may be due, at least in part, to polymorphisms in the...

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Share to CD3 Complex
Share to Genetic Predisposition to Disease
Share to Lupus Erythematosus, Systemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 23525753
DOI: 10.1093/rheumatology/ket119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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