Article
CD24 Ala/Val polymorphism and multiple sclerosis.
Journal of neuroimmunology - 1 Jun 2006
Goris An, Maranian Melanie, Walton Amie, Yeo Tai Wai, Ban Maria, Gray Julia, Dubois Bénédicte, Compston Alastair, Sawcer Stephen
Abstract excerpt
CD24 is expressed on a broad range of cells in the immune and central nervous systems and appears to be required for development of experimental autoimmune encephalomyelitis in mice. Association of a CD24 Ala/Val coding polymorphism with susceptibility to and progression of multiple sclerosis was recently reported. We typed this coding polymorphism in a combined cohort of 1,180 cases and 1,168 unrelated and...
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