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Article

Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project.

Gene - 15 Jul 2014

Pundhir Sachin, Hannibal Tine Dahlbæk, Bang-Berthelsen Claus Heiner, Wegener Anne-Marie Karin, Pociot Flemming, Holmberg Dan, Gorodkin Jan

Abstract excerpt

The Cd247 gene encodes for a transmembrane protein important for the expression and assembly of TCR/CD3 complex on the surface of T lymphocytes. Down-regulation of CD247 has functional consequences in systemic autoimmunity and has been shown to be associated with Type 1 Diabetes in NOD mouse. In...

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Share to CD3 Complex
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Mice, Inbred NOD

Share to Oligonucleotide Array Sequence Analysis

Share to Regulatory Sequences, Nucleic Acid

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Source

Identifiers

PMID: 24797614
DOI: 10.1016/j.gene.2014.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24797614-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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