Article
A dinucleotide deletion in CD24 confers protection against autoimmune diseases.
PLoS genetics - 6 Apr 2007
Wang Lizhong, Lin Shili, Rammohan Kottil W, Liu Zhenqiu, Liu Jin-qing, Liu Run-hua, Guinther Nikki, Lima Judy, Zhou Qunmin, Wang Tony, Zheng Xincheng, Birmingham Dan J, Rovin Brad H, Hebert Lee A, Wu Yeeling, Lynn D Joanne, Cooke Glenn, Yu C Yung, Zheng Pan, Liu Yang
Abstract excerpt
It is generally believed that susceptibility to both organ-specific and systemic autoimmune diseases is under polygenic control. Although multiple genes have been implicated in each type of autoimmune disease, few are known to have a significant impact on both. Here, we investigated the significance of polymorphisms in the human gene CD24 and the susceptibility to multiple sclerosis (MS) and systemic lupus...
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