IL28B genotype and the expression of ISGs in normal liver.

doi:10.1111/liv.12148

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Article

IL28B genotype and the expression of ISGs in normal liver.

Liver international : official journal of the International Association for the Study of the Liver - 1 Aug 2013

Raglow Zoe, Thoma-Perry Carly, Gilroy Richard, Wan Yu-Jui Y

Abstract excerpt

BACKGROUND & AIMS: Both polymorphisms in the IL28B gene locus and ISG expression levels are associated with the outcome of hepatitis C virus (HCV) infection. The two are also interrelated, although the mechanism is unknown. Favourable CC genotype at rs12979860 expresses lower baseline ISG levels and responds better to treatment than unfavourable CT and TT genotypes. Little is known about this relationship in...

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Identifiers

PMID: 23522062
DOI: 10.1111/liv.12148
PMCID: PMC7231429

Genes

BCL2
HTATIP2
ISG15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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