Article
IL28B is associated with outcomes of chronic HBV infection.
Yonsei medical journal - 1 May 2015
Shi Xiaodong, Chi Xiumei, Pan Yu, Gao Yanhang, Li Wanyu, Yang Chen, Zhong Jin, Xu Damo, Zhang Manna, Minuk Gerald, Jiang Jing, Niu Junqi
Abstract excerpt
PURPOSE: The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes. MATERIALS AND METHODS: IL28B genetic variations (rs12979860) were genotyped by pyrosequencing of DNA samples from 137 individuals with chronic HBV infection [50 inactive carriers (IC), 34...
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