Amyloid deposition in early onset versus late onset Alzheimer's disease.

doi:10.3233/JAD-121927

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Article

Amyloid deposition in early onset versus late onset Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Cho Hanna, Seo Sang Won, Kim Jung-Hyun, Suh Mee Kyung, Lee Jae-Hong, Choe Yearn Seong, Lee Kyung-Han, Kim Jae Seung, Kim Geon Ha, Noh Young, Ye Byoung Seok, Kim Hee Jin, Yoon Cindy W, Chin Juhee, Na Duk L

Abstract excerpt

BACKGROUND: Patients with early-onset Alzheimer's disease (EOAD) may differ from those with late-onset Alzheimer's disease (LOAD) in cognitive impairment profiles and clinical course. Postmortem studies also reported that EOAD has a greater pathologic burden than LOAD. We examined the effects of age at onset on the burden and distribution of amyloid plaques in patients with AD, using a statistical parametric...

Topics

Age of Onset
Aged
Aged, 80 and over
Alzheimer Disease
Amyloid
Aniline Compounds
Apolipoprotein E4
Data Interpretation, Statistical
Female
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Image Processing, Computer-Assisted

Magnetic Resonance Imaging

Male

Middle Aged

Neuropsychological Tests

Positron-Emission Tomography

Psychomotor Performance

Source

Open in PubMed

Identifiers

PMID: 23507771
DOI: 10.3233/JAD-121927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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