Article
Clinical and genetic markers associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes.
BMC infectious diseases - 20 Jan 2020
de Sá Nathalia Beatriz Ramos, Ribeiro-Alves Marcelo, da Silva Tatiana Pereira, Pilotto Jose Henrique, Rolla Valeria Cavalcanti, Giacoia-Gripp Carmem B W, Scott-Algara Daniel, Morgado Mariza Gonçalves, Teixeira Sylvia Lopes Maia
Abstract excerpt
BACKGROUND: Tuberculosis (TB) and AIDS are the leading causes of infectious disease death worldwide. In some TB-HIV co-infected individuals treated for both diseases simultaneously, a pathological inflammatory reaction termed immune reconstitution inflammatory syndrome (IRIS) may occur. The risk factors for IRIS are not fully defined. We investigated the association of HLA-B, HLA-C, and KIR genotypes with TB,...
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