Article
The rate and structural consequences of proline cis-trans isomerization in calbindin D9k: NMR studies of the minor (cis-Pro43) isoform and the Pro43Gly mutant.
Biochemistry - 8 May 1990
Kördel J, Forsén S, Drakenberg T, Chazin W J
Abstract excerpt
The EF-hand calcium-binding protein, calbindin D9k, exists in solution in the calcium-loaded state, as a 1:3 equilibrium mixture of two isoforms, the result of cis-trans isomerism at the Gly42-Pro43 peptide bond [Chazin et al. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 2195-2198]. Nuclear magnetic...
Topics
- Amino Acid Sequence
- Calbindins
- Calorimetry
- Isomerism
- Magnetic Resonance Spectroscopy
- Molecular Sequence Data
- Mutation
- Proline
- Protein Conformation
- S100 Calcium Binding Protein G