Article
Telomerase- and angiogenesis-related gene responses to irradiation in human umbilical vein endothelial cells.
International journal of molecular medicine - 1 May 2013
Chang Hyun, Rha Sun Young, Jeung Hei-Cheul, Park Kyu Hyun, Kim Tae Soo, Kim Yong-Bae, Chung Hyun Cheol
Abstract excerpt
In this study, we investigated the effects of ionizing radiation (IR) on human umbilical vein endothelial cells (HUVECs) in the context of senescence. HUVECs at passage number (PN)1, PN2 and PN3 were exposed to irradiation (2 Gy). The growth rate of the HUVECS was measured by proliferation assay and senescence-associated β-galactosidase assay was used to measure the number of senescent cells. Telomerase activity...
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