Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NEMO modulates radiation-induced endothelial senescence of human umbilical veins through NF-κB signal pathway.

Radiation research - 1 Jan 2015

Dong Xiaorong, Tong Fan, Qian Cai, Zhang Ruiguang, Dong Jihua, Wu Gang, Hu Yu

Abstract excerpt

Recently several laboratories have reported that radiation induces senescence in endothelial cells. Senescent cells can secrete multiple growth-regulatory proteins, some of which affect tumor growth, survival, invasion or angiogenesis. The purpose of this study was to explore the mechanisms of ra...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Senescence
Share to DNA Breaks, Double-Stranded
Share to Dose-Response Relationship, Radiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterocyclic Compounds, 3-Ring

Share to Human Umbilical Vein Endothelial Cells

Share to Neovascularization, Physiologic

Share to Pyridines

Share to Radiation Tolerance

Source

Identifiers

PMID: 25536232
DOI: 10.1667/RR13682.1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25536232-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NEMO modulates radiation-induced endothelial senescence of human umbilical veins through NF-κB signal pathway.PMID 25536232Read ↗

Characterization of DNA damage-induced cellular senescence by ionizing radiation in endothelial cellsSemantic proximity Read ↗

DNA damage response in vascular endothelial senescence: Implication for radiation-induced cardiovascular diseasesSemantic proximity Read ↗

Telomerase- and angiogenesis-related gene responses to irradiation in human umbilical vein endothelial cells.Semantic proximity Read ↗

Radiation-induced senescence-like phenotype in proliferating and plateau-phase vascular endothelial cellsSemantic proximity Read ↗

Deciphering the Dynamic Molecular Program of Radiation-Induced Endothelial Senescence.Semantic proximity Read ↗

GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cellsSemantic proximity Read ↗

Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low‐dose rate gamma radiationSemantic proximity Read ↗

Transcriptomic profiling and pathway analysis of cultured human lung microvascular endothelial cells following ionizing radiation exposureSemantic proximity Read ↗

[Role of endothelium in radiation-induced normal tissue damages].Semantic proximity Read ↗

Alteration of E2F2 Expression in Governing Endothelial Cell SenescenceSemantic proximity Read ↗

Transcriptomic profiling suggests a role for IGFBP5 in premature senescence of endothelial cells after chronic low dose rate irradiationSemantic proximity Read ↗

Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1 mediated signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.