Article
Modeling the influence of the A118G polymorphism in the OPRM1 gene and of noxious stimulation on the synergistic relation between propofol and remifentanil: sedation and analgesia in endoscopic procedures.
Anesthesiology - 1 Jun 2013
Borrat Xavier, Trocóniz Iñaki F, Valencia José F, Rivadulla Silvia, Sendino Oriol, Llach Josep, Muñoz Jenifer, Castellví-Bel Sergi, Jospin Mathieu, Jensen Erik W, Castells Antoni, Gambús Pedro L
Abstract excerpt
BACKGROUND: The presence of the A118G single nucleotide polymorphism in the OPRM1 gene as well as noxious stimulation might affect the requirements of remifentanil for patients undergoing ultrasonographic endoscopy under sedation-analgesia with propofol and remifentanil. Bispectral index (BIS) wa...
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