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Article

Delivery of alloantigens via apoptotic cells generates dendritic cells with an immature tolerogenic phenotype.

Transplantation proceedings - 1 Jan 2000

Gleisner M A, Rosemblatt M, Fierro J A, Bono M R

Abstract excerpt

BACKGROUND: Dendritic cells (DCs) are professional antigen-presenting cells able to induce immunity or tolerance. The interactions of immature DCs with naive T lymphocytes induce peripheral tolerance through mechanisms that include anergy or deletion of lymphocytes or the generation of regulatory T cells. Because of the central role of DCs in the immune response, they are potential targets for the induction of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21839264
DOI: 10.1016/j.transproceed.2011.06.007

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