Article
Genetic tagging shows increased frequency and longevity of antigen-presenting, skin-derived dendritic cells in vivo.
Nature immunology - 1 Sept 2003
Garg Sanjay, Oran Alp, Wajchman Janine, Sasaki Shin, Maris Charles H, Kapp Judith A, Jacob Joshy
Abstract excerpt
Dendritic cells (DCs) are key regulators of immune responses that activate naive antigen-specific T lymphocytes. In draining lymph nodes, antigen-bearing DCs are reported to be rare and short-lived. How such small numbers of short-lived DCs can activate rare antigen-specific T cells is unclear. H...
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