Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic expression analysis of the osteoarthritis susceptibility gene COL11A1 in human joint tissues.

BMC musculoskeletal disorders - 8 Mar 2013

Raine Emma V A, Dodd Andrew W, Reynard Louise N, Loughlin John

Abstract excerpt

BACKGROUND: The single nucleotide polymorphism (SNP) rs2615977 is associated with osteoarthritis (OA) and is located in intron 31 of COL11A1, a strong candidate gene for this degenerative musculoskeletal disease. Furthermore, the common non-synonymous COL11A1 SNP rs1676486 is associated with another degenerative musculoskeletal disease, lumbar disc herniation (LDH). rs1676486 is a C-T transition mediating its...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allelic Imbalance
Share to Cartilage, Articular
Share to Collagen Type XI
Share to Hip Joint
Share to Intervertebral Disc Displacement
Share to Knee Joint
Share to Osteoarthritis, Hip
Share to Osteoarthritis, Knee

Source

Open in PubMed Open full text

Identifiers

PMID: 23497244
DOI: 10.1186/1471-2474-14-85
PMCID: PMC3599795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic expression analysis of the osteoarthritis susceptibility gene COL11A1 in human joint tissues.PMID 23497244Read ↗

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritisSemantic proximity Read ↗

Annotating Transcriptional Effects of Genetic Variants in Disease‐Relevant Tissue: Transcriptome‐Wide Allelic Imbalance in Osteoarthritic CartilageSemantic proximity Read ↗

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis.Semantic proximity Read ↗

Allelic expression analysis of the osteoarthritis susceptibility locus that maps to chromosome 3p21 reveals cis-acting eQTLs at GNL3 and SPCS1.Semantic proximity Read ↗

Multi-Tissue Epigenetic and Gene Expression Analysis Combined With Epigenome Modulation Identifies RWDD2B as a Target of Osteoarthritis Susceptibility.Semantic proximity Read ↗

Large-scale gene expression in bone marrow mesenchymal stem cells: a putative role for COL10A1 in osteoarthritis.Semantic proximity Read ↗

Functional characterisation of the osteoarthritis susceptibility locus at chromosome 6q14.1 marked by the polymorphism rs9350591.Semantic proximity Read ↗

Identification of Long Noncoding RNA Associated with Osteoarthritis in HumansSemantic proximity Read ↗

A genetic variant in COL11A1 is functionally associated with lumbar disc herniation in Chinese population.Semantic proximity Read ↗

Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874.Semantic proximity Read ↗

Differential allelic expression of the type II collagen gene (COL2A1) in osteoarthritic cartilage.Semantic proximity Read ↗

Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilageSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.