Article
Large-scale gene expression in bone marrow mesenchymal stem cells: a putative role for COL10A1 in osteoarthritis.
Annals of the rheumatic diseases - 1 Oct 2010
Lamas José Ramón, Rodríguez-Rodríguez Luis, Vigo Ana G, Alvarez-Lafuente Roberto, López-Romero Pedro, Marco Fernando, Camafeita Emilio, Dopazo Ana, Callejas Sergio, Villafuertes Esther, Hoyas José Antonio, Tornero-Esteban María Pilar, Urcelay Elena, Fernández-Gutiérrez Benjamín
Abstract excerpt
OBJECTIVES: To elucidate disease-specific molecular changes occurring in osteoarthritis (OA) by analysing the differential gene expression profiles of bone marrow mesenchymal stem cells (BM-MSCs) from patients with OA compared with those without OA. METHODS: Expression profiles of BM-MSCs from eight paired patients with OA and patients with hip fracture without signs of OA were compared by DNA microarray...
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