A genetic variant in COL11A1 is functionally associated with lumbar disc herniation in Chinese population.

doi:10.1007/s12041-017-0874-8

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Article

A genetic variant in COL11A1 is functionally associated with lumbar disc herniation in Chinese population.

Journal of genetics - 1 Dec 2017

Liu Wenjun, Sun Guisen, Guo Longsheng, Wang Lulu, Fan Weiqiang, Lang Minglei, Chen Dan, Yi Xinhao

Abstract excerpt

This study aimed to explore whether the genetic variant of COL11A1 is functionally associated with the development of lumbar disc herniation (LDH) in Chinese population. SNP rs1676486 of COL11A1 was genotyped in 647 patients and 532 healthy controls. The differences of genotype and allele distributions between LDH patients and healthy controls were evaluated using the χ² test. One-way ANOVA test was used to...

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PMID: 29321344
DOI: 10.1007/s12041-017-0874-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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