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Article

Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators.

Journal of neuroinflammation - 12 Mar 2013

Suh Hyeon-Sook, Zhao Meng-Liang, Derico Leandra, Choi Namjong, Lee Sunhee C

Abstract excerpt

BACKGROUND: Recent studies in experimental animals show that insulin-like growth factor 1 (IGF1) plays a trophic role during development and tissue injury and that microglia are important sources of IGF1. However, little information is available regarding the expression, regulation, and function of IGF1 and related proteins in human brain cells. In the current study, we examined the expression of IGF1 and IGF2 in...

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Source

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Identifiers

PMID: 23497056
DOI: 10.1186/1742-2094-10-37
PMCID: PMC3607995

Genes

IGF1
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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