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Article

Regulation of hypoxia-induced inflammatory responses and M1-M2 phenotype switch of primary rat microglia by sex steroids.

Journal of molecular neuroscience : MN - 1 Feb 2014

Habib Pardes, Slowik Alexander, Zendedel Adib, Johann Sonja, Dang Jon, Beyer Cordian

Abstract excerpt

Microglia cells are the primary mediators of the CNS immune defense system and crucial for the outcome of shaping inflammatory responses. They are highly dynamic, moving constantly, and become activated by neuronal signaling under pathological conditions. They fulfill a dual role by not only regulating local neuroinflammation but also conferring neuronal protection. Gonadal steroids are known to exert...

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Identifiers

PMID: 24163150
DOI: 10.1007/s12031-013-0137-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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