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Article

Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver.

Pharmacogenetics and genomics - 1 May 2013

Webb Amy, Papp Audrey C, Sanford Jonathan C, Huang Kun, Parvin Jeffrey D, Sadee Wolfgang

Abstract excerpt

BACKGROUND: Membrane transporters control the influx and efflux of endogenous and xenobiotic substrates, including nutrients and drugs, across cellular membranes. OBJECTIVE: Whole transcriptome sequencing enables simultaneous analysis of overall and allele-specific mRNA expression, and the detection of multiple RNA isoforms. METHODS: Here we characterize variation in RNA transcripts emanating from gene loci...

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Identifiers

PMID: 23492907
DOI: 10.1097/FPC.0b013e32835ff536
PMCID: PMC4132188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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