Article
Pharmacogenomics of membrane transporters: past, present and future.
Pharmacogenomics - 1 Apr 2010
Yee Sook Wah, Chen Ligong, Giacomini Kathleen M
Abstract excerpt
Membrane transporters are major determinants of the absorption, distribution and elimination of many of the most commonly used drugs. In the past decade, the field of membrane transporter pharmacogenomics has undergone enormous growth. In particular, functional genomic and clinical studies have provided new information regarding the contribution of coding variants in transporters to drug disposition and response....
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