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Article

The effect of matrix metalloproteinase 2 and matrix metalloproteinase 2/9 deletion in experimental post-thrombotic vein wall remodeling.

Journal of vascular surgery - 1 Nov 2013

Deatrick Kristopher B, Luke Catherine E, Elfline Megan A, Sood Vikram, Baldwin Joseph, Upchurch Gilbert R, Jaffer Farouc A, Wakefield Thomas W, Henke Peter K

Abstract excerpt

BACKGROUND: Vein wall fibrotic injury following deep venous thrombosis (VT) is associated with elevated matrix metalloproteinases (MMPs). Whether and by what mechanism MMP2 contributes to vein wall remodeling after VT is unknown. METHODS: Stasis VT was produced by ligation of the inferior vena cava and tissue was harvested at 2, 8, and 21 days in MMP2 -/- and genetic wild type (WT) mice. Tissue analysis by...

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Source

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Identifiers

PMID: 23490298
DOI: 10.1016/j.jvs.2012.11.088
PMCID: PMC3688659

Genes

MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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