Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of cysteine-cysteine receptor 7 promotes fibrotic injury in experimental post-thrombotic vein wall remodeling.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2014

Laser Adriana, Elfline Megan, Luke Cathy, Slack Dallas, Shah Anuj, Sood Vikram, Deatrick Barry, McEvoy Brendan, Ostra Carson, Comerota Anthony, Kunkel Steven, Hogaboam Cory, Henke Peter K

Abstract excerpt

OBJECTIVE: Deep vein thrombosis (VT) can result in vein wall injury, which clinically manifests as post-thrombotic syndrome. Postinjury fibrosis may be modulated in part through cellular cysteine-cysteine receptor 7 (CCR7)-mediated events. We tested the hypothesis that late vein wall fibrotic remodeling is dependent on CCR7. APPROACH AND RESULTS: CCR7(-/-) and C57BL/6 wild-type mice had inferior vena cava VT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to Collagen Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type III

Share to Fibrosis

Share to Matrix Metalloproteinase 2

Share to Receptors, CCR7

Share to Tissue Culture Techniques

Share to Venous Thrombosis

Source

Open in PubMed Open full text

Identifiers

PMID: 24311382
DOI: 10.1161/ATVBAHA.113.302428
PMCID: PMC3904187

Genes

CCR7
DDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of cysteine-cysteine receptor 7 promotes fibrotic injury in experimental post-thrombotic vein wall remodeling.PMID 24311382Read ↗

A vein wall cell atlas of murine venous thrombosis determined by single-cell RNA sequencingSemantic proximity Read ↗

Tissue factor and thrombosis models.Semantic proximity Read ↗

Bone marrow-derived CCR5-expressing macrophages promote venous thrombus resolution by up-regulating plasminogen activators and VEGFSemantic proximity Read ↗

The effect of matrix metalloproteinase 2 and matrix metalloproteinase 2/9 deletion in experimental post-thrombotic vein wall remodeling.Semantic proximity Read ↗

Activated Endothelial TGFβ1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension.Semantic proximity Read ↗

Alterations in macrophage phenotypes in experimental venous thrombosis.Semantic proximity Read ↗

Gas6 Promotes Inflammatory (CCR2hiCX3CR1lo) Monocyte Recruitment in Venous Thrombosis.Semantic proximity Read ↗

Targeting pathogenic VWF/ADAMTS13 dysregulation attenuates CTEPH progressionSemantic proximity Read ↗

Mouse models of deep vein thrombosisSemantic proximity Read ↗

Murine models of vascular thrombosis (Eitzman series).Semantic proximity Read ↗

Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosisSemantic proximity Read ↗

Endothelial-specific deletion of autophagy-related 7 (ATG7) attenuates arterial thrombosis in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.