Article
Alterations in macrophage phenotypes in experimental venous thrombosis.
Journal of vascular surgery. Venous and lymphatic disorders - 1 Oct 2016
Gallagher Katherine A, Obi Andrea T, Elfline Megan A, Hogikyan Emily, Luke Catherine E, Henke Samuel, Coleman Dawn, Henke Peter K
Abstract excerpt
OBJECTIVE: Macrophages are involved in venous thrombus (VT) resolution and vein wall remodeling. This study was undertaken to identify variations in macrophage phenotypes in thrombi and vein wall in multiple models of VT to clarify the natural history of macrophage polarization in clearance of VT. We also sought to demonstrate the feasibility of macrophage phenotyping in human VT. METHODS: Established murine...
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