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Article

Cardiac Fibroblasts: Helping or Hurting

27 Mar 2025

Abstract excerpt

Cardiac fibroblasts (CFs) are the essential cell type for heart morphogenesis and homeostasis. In addition to maintaining the structural integrity of the heart tissue, muscle fibroblasts are involved in complex signaling cascades that regulate cardiomyocyte proliferation, migration, and maturation. While CFs serve as the primary source of extracellular matrix proteins (ECM), tissue repair, and paracrine...

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PMID: 40282342
DOI: 10.3390/genes16040381

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