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Direct Cardiac Reprogramming

12 Sept 2013

Abstract excerpt

Heart disease affects millions worldwide and is a progressive condition involving loss of cardiomyocytes. The human heart has limited endogenous regenerative capacity and is thus an important target for novel regenerative medicine approaches. Although cell-based regenerative therapies hold promise, cellular reprogramming of endogenous cardiac fibroblasts, which represent more than half of the cells in the...

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PMID: 24030021
DOI: 10.1161/circresaha.112.300625

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