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Article

Aspirin increases metabolism through germline signalling to extend the lifespan of Caenorhabditis elegans.

PloS one - 1 Jan 2017

Huang Xiao-Bing, Mu Xiao-Hui, Wan Qin-Li, He Xiao-Ming, Wu Gui-Sheng, Luo Huai-Rong

Abstract excerpt

Aspirin is a prototypic cyclooxygenase inhibitor with a variety of beneficial effects on human health. It prevents age-related diseases and delays the aging process. Previous research has shown that aspirin might act through a dietary restriction-like mechanism to extend lifespan. To explore the mechanism of action of aspirin on aging, we determined the whole-genome expression profile of Caenorhabditis elegans...

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PMID: 28910305
DOI: 10.1371/journal.pone.0184027
PMCID: PMC5598954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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