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AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets.

Molecular cell - 23 Jul 2004

Souret Frédéric F, Kastenmayer James P, Green Pamela J

Abstract excerpt

Messenger RNA degradation is an essential step in gene expression that can be regulated by siRNAs or miRNAs. However, most of our knowledge of in vivo eukaryotic mRNA degradation mechanisms derives from Saccharomyces cerevisiae, which lacks miRNAs and RNAi capability. Using reverse genetic and microarray analyses, we have identified multiple substrates of AtXRN4, the Arabidopsis homolog of the major yeast mRNA...

Topics

Arabidopsis
Arabidopsis Proteins
Exoribonucleases
Gene Expression Profiling
Gene Silencing
Leucine Zippers
MicroRNAs
Mutation
Oligonucleotide Array Sequence Analysis
Plant Proteins
Plants, Genetically Modified

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA Stability

RNA, Messenger

RNA, Plant

Saccharomyces cerevisiae

Source

Identifiers

PMID: 15260969
DOI: 10.1016/j.molcel.2004.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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