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Article

Effect of CYP2C9 and VKORC1 genetic polymorphisms on mean daily maintenance dose of acenocoumarol in South Indian patients.

Thrombosis research - 1 Apr 2013

Krishna Kumar Dhakchinamoorthi, Madhan Sivalingam, Balachander Jayaramen, Sai Chandran B V, Thamijarassy Bascarne, Adithan Chandrasekaran

Abstract excerpt

AIM: To determine the effect of CYP2C9 and VKORC1 genetic polymorphisms on mean daily maintenance dose of acenocoumarol in South Indian patients with heart valve replacement. MATERIALS AND METHODS: The study was conducted in 170 patients on therapy with acenocoumarol following heart valve replacement surgery. Single nucleotide polymorphisms (SNP) namely CYP2C9*2 (rs1799853), CYP2C9*3 (rs1057910), and VKORC1...

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Source

Identifiers

PMID: 23473641
DOI: 10.1016/j.thromres.2013.02.006

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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