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Article

Influence of genetics and non-genetic factors on acenocoumarol maintenance dose requirement in Moroccan patients.

Journal of clinical pharmacy and therapeutics - 1 Oct 2012

Smires F Z, Moreau C, Habbal R, Siguret V, Fadili S, Golmard J L, Assaidi A, Beaune P, Loriot M A, Nadifi S

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Coumarin derivatives such as acenocoumarol represent the therapy of choice for the long-term treatment and prevention of thromboembolic diseases. Many genetic, clinical and demographic factors have been shown to influence the anticoagulant dosage. Our aim was to investigate the contribution of genetic and non-genetic factors to variability in response to acenocoumarol in Moroccan...

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Source

Identifiers

PMID: 22486182
DOI: 10.1111/j.1365-2710.2012.01340.x

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of genetics and non-genetic factors on acenocoumarol maintenance dose requirement in Moroccan patients.PMID 22486182Read ↗

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