Article
An acenocoumarol dosing algorithm exploiting clinical and genetic factors in South Indian (Dravidian) population.
European journal of clinical pharmacology - 1 Feb 2015
Krishna Kumar Dhakchinamoorthi, Shewade Deepak Gopal, Loriot Marie-Anne, Beaune Philippe, Sai Chandran B V, Balachander Jayaraman, Adithan Chandrasekaran
Abstract excerpt
OBJECTIVE: The objective of this study was to determine the influence of CYP2C9, VKORC1, CYP4F2, and GGCX genetic polymorphisms on mean daily dose of acenocoumarol in South Indian patients and to develop a new pharmacogenetic algorithm based on clinical and genetic factors. METHODS: Patients rece...
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