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Article

Contribution of V(H) replacement products in mouse antibody repertoire.

PloS one - 1 Jan 2013

Huang Lin, Lange Miles D, Yu Yangsheng, Li Song, Su Kaihong, Zhang Zhixin

Abstract excerpt

VH replacement occurs through RAG-mediated recombination between the cryptic recombination signal sequence (cRSS) near the 3' end of a rearranged VH gene and the 23-bp RSS from an upstream unrearranged VH gene. Due to the location of the cRSS, VH replacement leaves a short stretch of nucleotides from the previously rearranged VH gene at the newly formed V-D junction, which can be used as a marker to identify VH...

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Source

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Identifiers

PMID: 23469094
DOI: 10.1371/journal.pone.0057877
PMCID: PMC3585286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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