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Article

Behavioral and pharmacological phenotypes of brain-specific diacylglycerol kinase δ-knockout mice.

Brain research - 1 Oct 2016

Usuki Takako, Takato Tamae, Lu Qiang, Sakai Hiromichi, Bando Kana, Kiyonari Hiroshi, Sakane Fumio

Abstract excerpt

Diacylglycerol kinase (DGK) is a lipid-metabolizing enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Previously, we reported that the δ isozyme of DGK was abundantly expressed in the mouse brain. However, the functions of DGKδ in the brain are still unclear. Because conventional DGKδ-knockout (KO) mice die within 24h after birth, we have generated brain-specific conditional DGKδ-KO mice to...

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Identifiers

PMID: 27423518
DOI: 10.1016/j.brainres.2016.07.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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