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Article

Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23.

Cell - 11 Jul 2003

Sørensen Jakob B, Nagy Gábor, Varoqueaux Frederique, Nehring Ralf B, Brose Nils, Wilson Michael C, Neher Erwin

Abstract excerpt

The SNARE complex, consisting of synaptobrevin, syntaxin, and SNAP-25, is essential for calcium-triggered exocytosis in neurosecretory cells. Little is known, however, about how developmentally regulated isoforms and other cognate SNARE components regulate vesicular fusion. To address this question, we examined neuroexocytosis from chromaffin cells of Snap25 null mice rescued by the two splice variants SNAP-25a...

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Source

Identifiers

PMID: 12859899
DOI: 10.1016/s0092-8674(03)00477-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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