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Article

Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Mar 2013

Dzirasa Kafui, Kumar Sunil, Sachs Benjamin D, Caron Marc G, Nicolelis Miguel A L

Abstract excerpt

Although the majority of first-line antidepressants increase brain serotonin and rare polymorphisms in tryptophan hydroxlase-2 (Tph2), the rate-limiting enzyme in the brain serotonin synthesis pathway, have been identified in cohorts of subjects with major depressive disorder, the circuit level a...

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Identifiers

PMID: 23467366
DOI: 10.1523/JNEUROSCI.4891-12.2013
PMCID: PMC3633471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23467366-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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