Article
The SWI/SNF chromatin remodeling complex selectively affects multiple aspects of serotonergic neuron differentiation.
Genetics - 1 May 2013
Weinberg Peter, Flames Nuria, Sawa Hitoshi, Garriga Gian, Hobert Oliver
Abstract excerpt
Regulatory programs that control the specification of serotonergic neurons have been investigated by genetic mutant screens in the nematode Caenorhabditis elegans. Loss of a previously uncloned gene, ham-3, affects migration and serotonin antibody staining of the hermaphrodite-specific neuron (HSN) pair. We characterize these defects here in more detail, showing that the defects in serotonin antibody staining are...
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